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2021

32. E. D. M. Isa, H. Ahmad, M. B. A. Rahman, M. R. Gill, Progress in mesoporous silica nanoparticles as drug delivery agents for cancer treatment, Pharmaceutics, 2021, 13, 152. https://www.mdpi.com/1999-4923/13/2/152

31. S. N. Harun, H. Ahmad, H. N. Lim, S. L. Chia, M. R. Gill, Synthesis and optimization of mesoporous silica nanoparticles for ruthenium polypyridyl drug delivery, Pharmaceutics, 2021, 13, 150. https://www.mdpi.com/1999-4923/13/2/150

2020

30. N. A. Yusoh, H. Ahmad, M. R. Gill, Combining PARP inhibition with platinum, ruthenium or gold metal complexes for cancer therapy, ChemMedChem, 2020, 15, 2121-2135.

https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.202000391

29. M. R. Gill, M. G. Walker, S. Able, Ole Tietz, A. Lakshminarayanan, R. Anderson, R. Chalk, A. H. El-Sagheer, T. Brown, J. A. Thomas, K. A. Vallis, An 111In-labelled bis-ruthenium(II) dipyridophenazine theranostic complex: Mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells. Chem Sci, 2020, 11, 8936-8944. 

https://pubs.rsc.org/en/content/articlelanding/2020/sc/d0sc02825h#!divAbstract

28. N. A. Yusoh, S. W. Leong, S. L. Chia, S. N. Harun, M. B. A. Rahman, K. A. Vallis, M. R. Gill, H. Ahmad, The metallo-intercalator [Ru(dppz)2(PIP)]2+ renders BRCA wild-type triple-negative breast cancer cells hypersensitive to PARP inhibition, ACS Chem Biol, 2020, 15, 378-387. https://pubs.acs.org/doi/10.1021/acschembio.9b00843

27. J. Owen, E. Thomas, J. Menon, M. Gray, I. Skaripa-Koukelli, M. R. Gill, S. Wallington, R. L. Miller, K. A. Vallis, R. Carlisle, Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation, J Control Release, 2020, 319, 222-233. https://www.sciencedirect.com/science/article/abs/pii/S0168365919307643

2019

26. M. R. Jackson, B. M. Bavelaar, P. A. Waghorn, M. R. Gill, A. H. El-Sagheer, T. Brown, M. Tarsounas, K. A. Vallis, Dual-action 111In-labelled oligonucleotides against the RNA subunit of telomerase inhibit enzymatic activity and are radiotoxic against telomerase-positive cancer cells, Cancer Res, 2019, 79, 4627-4637. https://cancerres.aacrjournals.org/content/79/18/4627

25. P. Brown, RELISH consortium, Y. Zhou, Large expert-curated database for benchmarking document similarity detection in biomedical literature search, Database, 2019, 1-66.

24. Y. Zhu, M. Zhang, L. Luo, M. R. Gill, C. De Pace, G. Battaglia, Q. Zhang, H. Zhou, J. Wu, T. Tian, X. Tian, NF-kB hijacking theranostic Pt(II) complex in cancer therapy, Theranostics, 2019, 9, 2158-2166. https://www.thno.org/v09p2158

23. K. Smitten, H. Southam, J. Bernardino de la Serna, M. R. Gill, P. Jarman, C. Smythe, R. Poole, J. A. Thomas, Using nanoscopy to probe the biological activity of antimicrobial lead compounds that display potent activity against pathogenic, multi-drug resistant, Gram-negative bacteria, ACS Nano, 2019, 13, 5133-5146. https://pubs.acs.org/doi/10.1021/acsnano.8b08440

22. M. R. Gill and K. A. Vallis, Transition metal compounds as cancer radiosensitizers, Chem. Soc. Rev, 2019, 48, 540 – 557.  

https://pubs.rsc.org/en/content/articlelanding/2019/cs/c8cs00641e#!divAbstract

 

2018

21. B. M. Bavelaar, B. Q. Lee, M. R. Gill, N. Falzone, K. A. Vallis, Subcellular targeting of theranostic radionuclides, Front. Pharmacol., 2018, 9, 996. 

https://www.frontiersin.org/articles/10.3389/fphar.2018.00996/full

20. M. R. Gill,† J. U. Menon,† P. Jarman, J. Owen, I. Sharipa-Koukelli, S. Able, J. A. Thomas, R. Carlisle, K. A. Vallis, 111In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells, Nanoscale, 2018, 10, 10596-10608.

https://pubs.rsc.org/en/content/articlelanding/2018/nr/c7nr09606b#!divAbstract

19. M. R. Gill, P. Jarman, S. Halder, M.G. Walker, J. A. Thomas, C. Smythe, K. Ramadan, K. A. Vallis, A three-in-one bullet for oesophageal cancer: Replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(II) metallo-intercalator, Chem. Sci., 2018, 9, 841-849. https://pubs.rsc.org/en/content/articlelanding/2018/sc/c7sc03712k#!divAbstract

2007-2017

18. S. Sreedharan, M. R. Gill, E. Garcia, H. K. Saeed, D. Robinson, A. Byrne, A. Cadby, T. E. Keyes, C. Smythe, P. Pellett, J. B. de la Serna, J. A. Thomas, Multimodal super-resolution optical microscopy using a transition metal-based probe provides unprecedented capabilities for imaging both nuclear chromatin and mitochondria, J. Am. Chem. Soc., 2017, 139, 15907–15913. https://pubs.acs.org/doi/abs/10.1021/jacs.7b08772

17. M. R. Gill, N. Falzone, Y. Du, K. A. Vallis, Targeted radionuclide therapy in combined-modality regimens, Lancet Oncol., 2017, 18, e414–e423. 

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(17)30379-0/fulltext

16. M. R. Gill, S. N. Harun, S. Halder, R. A. Boghozian, K. Ramadan, H. Ahmad, K. A. Vallis, A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition, Sci. Rep., 2016, 6, 31973. 

https://www.nature.com/articles/srep31973

15. M. G. Walker, P. J. Jarman, M. R. Gill, X. Tian, H. Ahmad, P. A. N. Reddy, L. McKenzie, J. A. Weinstein, A. J. R. Meijer, G. Battaglia, C. Smythe and J. A. Thomas, A self-assembled metallomacrocycle singlet oxygen sensitizer for photodynamic therapy, Chem. Eur. J., 2016, 22, 5996-6000. https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.201600852

14. A. Wragg,† M. R. Gill,† L. McKenzie, C. Glover, R. Mowll, X. Su, C. Smythe and J. A. Thomas, Serum albumin binding inhibits nuclear uptake of luminescent metal complex-based DNA imaging probes, Chem. Eur. J., 2015, 21, 11865-11871. 

https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.201501675

13. V. Ramu,† M. R. Gill,† P. J. Jarman, D. Turton, J. A. Thomas, A. Das and C. Smythe, A cytostatic ruthenium(II)-platinum(II) bis(terpyridyl) anticancer complex that blocks entry into S phase through up-regulating p27KIP1, Chem. Eur. J., 2015, 21, 9185-9197. 

https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.201500561

12. A. Wragg,† M. R. Gill,† D. Turton, H. Adams, C. Smythe, X. Su and J. A. Thomas, Tuning the cellular uptake properties of luminescent heterobimetallic iridium(III)-ruthenium(II) DNA imaging probes, Chem. Eur. J., 2014, 20, 14004-14011. 

https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.201403693

11. A. Wragg, M. R. Gill, C. J. Hill, X. Su, A. J. H. M. Meijer, C. Smythe and J. A. Thomas, Dinuclear osmium(II) probes for high-resolution visualisation of cellular DNA structure using electron microscopy, Chem. Commun., 2014, 50, 14494-14497 (front cover). 

https://pubs.rsc.org/en/content/articlelanding/2014/cc/c4cc05547k#!divAbstract

10. E. Baggaley, M. R. Gill, N. H. Green, D. Turton, I. V. Sazanovich, S. W. Botchway, C. Smythe, J. W. Haycock, J. A. Weinstein, J. A. Thomas, Dinuclear ruthenium(II) complexes as two-photon, time-resolved emission microscopy probes for cellular DNA, Angew. Chem. Int. Ed., 2014, 53, 3367-3371 (front cover; Faculty of 1000 recommended article). 

https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201309427

9. M. R. Gill, D. Cecchin, M. G. Walker, R. S. Mulla, G. Battaglia, C. Smythe and J. A. Thomas, Targeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(II) polypyridyl complex, Chem. Sci., 2013, 4, 4512-4519. (referee-recommended "hot article"). https://pubs.rsc.org/en/content/articlelanding/2013/SC/c3sc51725j#!divAbstract

8. M. R. Gill and J. A. Thomas, Ruthenium(II) polypyridyl complexes and DNA: from structural probes to cellular imaging and therapeutics, Chem. Soc. Rev., 2012, 41, 3179-3192.  

https://pubs.rsc.org/en/content/articlelanding/2012/CS/c2cs15299a#!divAbstract

7. M. R. Gill, H. Derrat, C. Smythe, G. Battaglia and J. A. Thomas, Ruthenium(II) metallo-intercalators: DNA imaging and cytotoxicity, ChemBioChem, 2011, 12, 877-880 (a ChemBioChem “most cited” article 2012-13). 

https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201000782

6. X. Tian, M. R. Gill, I. Canton, J. A. Thomas and G. Battaglia, Live cell luminescence imaging as a function of delivery mechanism, ChemBioChem, 2011, 12, 548-551. https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201000743

5. A. Ghosh, P. Das, M. R. Gill, P. Kar, M. G. Walker, J. A. Thomas and A. Das, Photoactive RuII–Polypyridyl Complexes that Display Sequence Selectivity and High-Affinity Binding to Duplex DNA through Groove Binding, Chem. Eur. J., 2011, 17, 2089-2098 (inside cover). https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.201002149

4. P. Waywell, V. Gonzalez, M. R. Gill, H. Adams, A. J. H. Meijer, M. P. Williamson and J. A. Thomas, Structure of the Complex of [Ru(tpm)(dppz)py]2+ with a B-DNA Oligonucleotide - A Single-Substituent Binding Switch for a Metallo-Intercalator, Chem. Eur. J., 2010, 16, 2407-2417. (inside cover). https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.200901758

3. M. R. Gill, J. Garcia-Lara, S. J. Foster, C. Smythe, G. Battaglia and J. A. Thomas, A ruthenium(II) polypyridyl complex for direct imaging of DNA structure in living cells, Nature Chem., 2009, 1, 662-667. https://www.nature.com/articles/nchem.406

2. S. P. Foxon, T. Phillips, M. R. Gill, M. Towrie, A. W. Parker, M. Webb and J. A. Thomas, A Multifunctional Light Switch: DNA Binding and Cleavage Properties of a Heterobimetallic Ruthenium-Rhenium Dipyridophenazine Complex, Angew. Chem. Int. Ed., 2007, 46, 3686-3688. https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.200604837

1. C. J. Adams, J. P. H. Charmant, N. G. Connelly, M. Gill, A. Kantacha, S. Onganusorn and A. G. Orpen, Homobinuclear cyanide-bridged linkage isomers containing the redox-active unit [([μ]-XY)Ru(CO)2L(o-O2C6Cl4)] (XY = CN or NC), Dalton Trans., 2007, 2283-2294. https://pubs.rsc.org/en/content/articlelanding/2007/dt/b700648a#!divAbstract

Book chapters:

M. R. Gill and J. A. Thomas, Targeting cellular DNA with luminescent ruthenium(II) polypyridyl complexes,  in Ruthenium Complexes -  Photochemical and Biomedical Applications, eds. A. Holder, J. L. Bullock, M. A. Lawrence, W. R. Browne and L. Lilge, Wiley-VCH, 2018.